The DMK's opposition to the National Eligibility-cum-Entrance Test (NEET) in Tamil Nadu is driven by concerns over disadvantages faced by rural and disadvantaged students, language barriers, stress-related student suicides, curriculum misalignment, impact on the state's education system, and its political implications. The party seeks to safeguard Tamil Nadu's educational values, equal access to quality education, and autonomy over education policies while advocating for alternatives that cater to the state's unique needs.