Biotech enigma: On the BioE3 proposal and beyond
Biotechnology initiatives need long-term capital investments
Earlier this week the Cabinet cleared a proposal, though without specifying a budget, called BioE3 or Biotechnology for Economy, Environment and Employment. Its thrust is to boost manufacturing in the biotechnology sector. Since 1986, India has had a dedicated department for biotechnology, and which deserves substantial credit. For instance, the progress in vaccine development, diagnostics and biologicals, that has bolstered India’s reputation as a ‘vaccine factory’, is due to the initiatives of this department. However, biotechnology did not quite spawn the equivalent of the IT revolution. There is much more to an industrialised biotechnology sector beyond vaccines. There are billion-dollar conglomerates today that rest on high-value microbes, gene-modification technologies, bio-plastics, bio-materials, and high-precision medical devices. However, despite the know-how and human resource capital, only a few Indian biotechs have global resonance, as there are few local manufacturers who can supply Indian laboratories/startups with the ingredients and devices to make products. The reliance on imports means that India loses its international competitiveness. The BioE3 policy aims to correct this.In the last four decades, India has funded biotech research institutions but now sees that it needs to be going beyond and setting up companies, in public private partnership mode, to bolster biotechnology manufacturing. There are six verticals that this initiative envisages: bio-based chemicals and enzymes; functional foods and smart proteins; precision biotherapeutics; climate-resilient agriculture; carbon capture, and futuristic marine and space research. Futurists have been saying that the era of fossil-fuel industrialisation is over and humanity will have to rely on the natural world — for food and for making consumer products. This is to solve the global problem of non-biodegradable waste and carbon emissions. Future industries must be grounded in environmentally benign products, and this is impossible without sophisticated biotechnology. By setting up bio-foundries and bio-artificial intelligence hubs, the policy hopes there will be avenues for a variety of biotechnologists to congregate. Well intentioned this may be, but India’s woes with manufacturing have chronic causes. Without establishing enabling grounds for long-term capital investment — and these have little to do with biotechnology per se — top-down initiatives will have limited impact. The BioE3 policy must be a deeply collaborative effort between Centre and States. Rather than expect quick returns, the government must provide financial and infrastructural support over the long term.